Traveling by train from Rome to Milan is an easy and comfortable way to explore Italy’s varied and scenic landscapes. The distance from Rome to Milan is 297 miles and many high-speed trains make the trip in just 2 hours and 55 minutes. 

Enjoy a journey that tracks north through Italy’s breathtaking Emilia-Romagna and Lombardy regions, with a stop in Bologna. Most high-speed trains travel directly from Rome to Milan and you won’t be required to change trains. However, if you’re traveling on a slower and less expensive regional train, you may be required to transfer from one train to another.

Trains leave Rome Termini station several times per hour for Milan Centrale Station — averaging 65 trains per day. The earliest train leaves Rome Termini station at 6:00 a.m. The last train to Milan leaves Rome at 11:50 p.m. 

Note that weekends and holidays typically mean less frequent service and sometimes longer travel times.

Many of the high-speed trains make the journey between Rome and Milan in just 2 hours and 55 minutes, traveling up to 155 miles per hour.

Italy’s high-speed trains are equipped with air conditioning and electrical outlets at your seat to charge devices. There is wi-fi on trains, but the signal will drop in tunnels and at stations. Expect a cafe car on every train, as well as food cart that brings snacks, sandwiches and beverages to your seat. At the end of each car you’ll find a restroom and plenty of racks to store large luggage.